Research

We are an interdisciplinary research group. Our research efforts have been focusing on defining the efficacies of preventive and therapeutic approaches (drugs, exercise, and gene delivery) for mitochondrial dysfunction in multiple disease conditions. 

 

Research Topics

  1. To study the underlying mechanisms and potential treatment in the pathological developments (neurological dysfunction, cardiomyopathy, and muscle weakness) of Friedreich’s ataxia.

  • DOD/CDMRP (PI): 11/2023 – 11/2025

  • NIH/NINDS/R21 (Co-I): 4/2022 – 3/2025

  • UML Seed Grant (PI): 7/2023 – 6/2025

  1. To study mitochondrial iron export therapy for doxorubicin-induced cardiotoxicity.

  • NIH/NHLBI/R01 (Co-I): 1/2023 – 12/2026

  1. To study preventive strategy for mitochondrial copper cumulation in Wilson’s disease.

  • NIH/NICHD/R21 (Co-I): 9/2022 – 8/2024