Seongkyu Yoon

Our group’s mission is to accelerate biopharmaceutical manufacturing innovation, support the development of standards that enable more efficient and rapid manufacturing capabilities, and educate and train a world-leading biopharmaceutical manufacturing workforce, fundamentally advancing U.S. competitiveness in this industry. We also focus our efforts on driving down the costs and risks associated with manufacturing biologics including proteins, cell based therapeutics and vectored gene therapies. 

Affliated Websites                   

Recent News

  • February 2024: Congratulations Yongdan and Qiang along with co-authors, Soyoung Park, Seo-young Park, Yong Suk Lee, and Dr. Dongyup Lee. The review paper was accepted for publication in the Journal of Biotechnology Advances with the title of Decoding Cellular Mechanism of Recombinant Adeno-associated Virus (rAAV) and Engineering Host-Cell Factories toward Intensified Viral Vector Manufacturing. This review paper proposes a control strategy from the perspectives of host cell and materials (e.g., AAV plasmids) based on the characterization of molecular features and our existing knowledge of the AAV viral life cycle, rAAV and other viral vector productions in the human embryonic kidney (HEK) cells.

 

  • January 2024: Welcome Dr. Younyoung Choi, post-doctoral fellow and Dr. Tom Bertalan, research engineer to the group. They will lead digital twin and upstream biotherapeutics development projects. 

 

  • January 2024: Welcome Zahra (started in the Spring Semester 2024 in Pharmaceutical Sciences program) and Kanika (started in the Fall semester 2023 as a PhD student in BMEBT program) as new PhD students. 

 

  • January 2024: Haenah Kim and Hung Tran are doing PhD student industrial experiences at Takeda Pharmaceutical. The fellowship will be done over 6 months. This is NSF funded industrial experience program.  

 

  • January 2024: Richard Marx awarded KFF fellowship ($12K). This is a prestigious award to be given to PhD student who has successfully defended a research proposal. 

 

  • January 2024: Congratulation Richard on the publication. The manuscript was accepted for publication in the Biotechnology Journal with the title of CFD evaluation of hydrophobic feedstock bench-scale fermenters for efficient high agitation volumetric mass transfer. This research paper is based on a NSF-funded project led by Prof Dongming Xie.