Seongkyu Yoon

Welcome to the systems biology laboratory (SBL) Website!

Our group’s mission is to accelerate biopharmaceutical manufacturing innovation, support the development of standards that enable more efficient and rapid manufacturing capabilities, and educate and train a world-leading biopharmaceutical manufacturing workforce, fundamentally advancing U.S. competitiveness in this industry. We also focus our efforts on driving down the costs and risks associated with manufacturing biologics including proteins, cell based therapeutics and vectored gene therapies. 

Affliated Websites                   

Recent News

  • May 2021: Congratulations to Dr. Graham, Dr. Kamga and Dr. Kuang!
  • September 2020: Congratulations to SoYoung Park and Yongdan Wang for being admitted to our Ph.D. program! 
  • February 2020: Our “Biomanufacturing Professional Training Series, 2020” just went live and is currently opened for registration! Please head over here for our current and upcoming events, including dates and registration link. For further detail regarding each short course, including course outline and description, please refer to our short course description page.
  • January 2020: We just wrapped up our AMBIC December meeting! Much thanks to the University of Maryland – College Park for hosting the event. We received continuous funding from the AMBIC industrial members on the following four projects that we are working on (two of which are continuous ongoing projects): i) Inhibitor Waste Metabolites, ii) Gene Therapy (Adeno-Associated Virus Production) and iii) Genome Scale Modelling.
  •  November 2019: We are proud to announce that the case study on modelling flowsheet of a tablet manufacturing process using gPROMS presented by Dr. Galbraith: “Integrated modelling of a continuous direct compression tablet manufacturing process: A production scale case study” recently won the 2019 PSE Model-Based Innovation Prizes. Congratulations!
  • September 2019: Congratulations to Richard Marx and Qiang Fu for being admitted to our Ph.D. program! 
  • June 2019: We just wrapped up the June 2019 AMBIC meeting. All of our current projects were on track and received positive feedback from the industrial members. 
  • January 2019: We are happy to announce that UMass Lowell will be the lead of the mAB Project “Monoclonal antibody (mAb) productivity improvement by metabolic engineering of novel inhibitory biomarker in integrated continuous manufacturing.” This project will be funded by the National Institute for Innovation in Manufacturing Biopharmaceuticals  (NIIMBL). We will be collaborating with Genentech, Merck & Co, ImmunoGen, Massachusetts Life Sciences Center, and Johns Hopkins University.
  • October 2018: We just recently wrapped up our Bio Summit event on “Biomanufacturing Innovation”. Great job everyone!
  • Archived News